A blast in the Pakistani city of Quetta in Baluchistan province has killed at least 10 people and left many others seriously wounded, reports say.
According to ISPR, an army truck was the main target of the terrorists.
"Our resolve won't succumb to any challenge", he said in a statement.
Bugti said rescue had begun as the area targeted in the blast caught fire soon after the explosion. "Investigations are continuing but I can confirm it was a big explosion and there are around two dozen injured who are being shifted to nearby hospitals", Bugti said.
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The U.S., China and Russian Federation need to come together to force the North to de-escalate, he said. President Donald Trump has issued tough warnings to North Korea in response.
Casualties were also confirmed by rescue and hospital sources.
The Inter-Services Public Relations (ISPR), media wing of the army, confirmed a vehicle of security forces was targeted in the blast that martyred 15 people including seven citizens.
Army troops reached incident site and cordoned off the area. The injured people were taken to a Civil Hospital in Quetta.
Speaking to Geo News, provincial Home Minister Sarfaraz Bugti said the explosion was intense and the death toll could rise further.
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Beijing's appeal came as North Korea said it could reduce the US mainland to ashes "at any moment". "That was one of those I wish I'd not said ", Ellison said.
At least 25 people have also been reported as injured in the blast that set multiple cars on fire.
The nature of the explosion could not be immediately ascertained; however, eyewitnesses said that the explosion had occurred near a security forces vehicle.
But The Bomb Disposal Squad said the blast was carried out by a suicide bomber.
FC Hostel and the Balochistan Assembly are near the spot of the explosion and the area is categorised as sensitive.
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Daesh, a Takfiri terrorist group which mainly operates in the Middle East but has also established a branch in Afghanistan, has claimed several attacks in the Pakistani territory in the recent past.