Coming off their worst defeat of the season - a 6-0 loss to Bayern Munich - Hamburg, who face their first-ever relegation from Germany's top league, announced on their website that they have sacked Bernd Hollerbach just seven games after appointing him.
The 48-year-old coach has been relived from all his duties as Hamburg's Under-21 coach Christian Titz has been appointed until the end of the season.
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Hollerbach, a former Hamburg midfielder, failed to win any of his seven league games in charge since taking over from the sacked Gisdol on January 22, falling to four losses and claiming only three points.
Hamburg is the only Bundesliga club that never relegated into the second division.
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"We analyzed and discussed the overall sporting situation after the 6-0 defeat in Munich", said former deputy chairman Frank Wettstein, who took over the operative leadership at the club while it seeks a replacement for Bruchhagen. "In the end, looking at our chances for survival, we had to react".
"He never complained and behaved impeccably. But the bottom line was that there was no significant improvement and he failed to gain positive results".
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Titz was to take charge of Tuesday's training in preparation for Saturday's visit by Hertha Berlin.