The prison in Bishopville, South Carolina, about 60 miles northeast of Columbia, houses about 1,600 male inmates, according to the state's corrections department.
Taillon said multiple inmate fights broke out at 7:15 p.m. Sunday.
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South Carolina Department of Corrections did not immediately return a request for comment Monday morning.
Lee County Fire/Rescue said ambulances from at least seven jurisdictions lined up outside the prison to tend to the wounded.
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Some local media outlets reported the local coroner had been called to the scene. Two officers were stabbed in a 2015 fight.
COLUMBIA, S.C. (AP) State police have been called to one of South Carolina's most unsafe prisons.
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They say the incident resulted in 17 inmates requiring outside medical attention and seven inmates were killed. Four inmates were killed by a pair of prisoners in the state's Kirkland Correctional Institution a year ago.